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Lung cancer drugs
Seeing a long list of drug names can feel overwhelming. Here they're grouped the way care teams usually think about them, so you and your family can find where you are.
ℹ️ General information to help you and your loved ones talk with your care team, not medical advice. Read our disclaimer.
Drugs by line of therapy
Which line a drug is used in depends on your cancer's stage, biomarkers, earlier treatment and overall health. Your care team will decide what's right for you. Many drugs are used in more than one line.
🌱 Early-stage (before or after surgery)
1️⃣ First-line for advanced cancer
2️⃣ Second-line
Browse lung cancer drug guides
Alecensa (alectinib)Targeted therapy pill (ALK inhibitor)Alimta (pemetrexed)Chemotherapy (antifolate)Alunbrig (brigatinib)Targeted therapy pill (ALK inhibitor)Augtyro (repotrectinib)Targeted therapy pill (ROS1/NTRK inhibitor)Avastin (bevacizumab)Targeted therapy (VEGF antibody)Braftovi (encorafenib)Targeted therapy pill (BRAF inhibitor)CarboplatinChemotherapy (platinum drug)CisplatinChemotherapyEnhertu (fam-trastuzumab deruxtecan)Antibody-drug conjugate (HER2-directed)EtoposideChemotherapyGavreto (pralsetinib)Targeted therapy pill (RET inhibitor)Gemzar (gemcitabine)ChemotherapyGilotrif (afatinib)Targeted therapy pill (EGFR inhibitor)Imdelltra (tarlatamab)Bispecific T-cell engager (DLL3)Imfinzi (durvalumab)Immunotherapy (PD-L1 blocker)Iressa (gefitinib)Targeted therapy pill (EGFR inhibitor)Keytruda (pembrolizumab)Immunotherapy (PD-1 blocker)Krazati (adagrasib)Targeted therapy pill (KRAS G12C inhibitor)Lazcluze (lazertinib)Targeted therapy pill (EGFR inhibitor)Libtayo (cemiplimab)Immunotherapy (PD-1 blocker)Lorbrena (lorlatinib)Targeted therapy pill (ALK inhibitor)Lumakras (sotorasib)Targeted therapy pill (KRAS G12C inhibitor)Mekinist (trametinib)Targeted therapy pill (MEK inhibitor)Opdivo (nivolumab)Immunotherapy (PD-1 blocker)Retevmo (selpercatinib)Targeted therapy pill (RET inhibitor)Rozlytrek (entrectinib)Targeted therapy pill (ROS1/NTRK inhibitor)Rybrevant (amivantamab)Targeted antibody (EGFR and MET)Tabrecta (capmatinib)Targeted therapy pill (MET inhibitor)Tafinlar (dabrafenib)Targeted therapy pill (BRAF inhibitor)Tagrisso (osimertinib)Targeted therapy pill (EGFR inhibitor)Tarceva (erlotinib)Targeted therapy pill (EGFR inhibitor)Taxol (paclitaxel)Chemotherapy (taxane)Tecentriq (atezolizumab)Immunotherapy (PD-L1 blocker)Tepmetko (tepotinib)Targeted therapy pill (MET inhibitor)Vitrakvi (larotrectinib)Targeted therapy pill (TRK inhibitor)Vizimpro (dacomitinib)Targeted therapy pill (EGFR inhibitor)Yervoy (ipilimumab)Immunotherapy (CTLA-4 blocker)Zepzelca (lurbinectedin)Chemotherapy
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Written by the Cancer Side Effects Guide team from FDA labels and leading cancer centers. Not medical advice. · Last updated: October 15, 2026 · How we write
Not medical advice. This page is general information to help you talk with your care team. It can't replace advice from your doctor or nurse. If you have a fever of 100.4°F (38°C) or higher during treatment, or any symptom that worries you, call your care team now. In an emergency, call 911.