Prostate cancer drugs

Seeing a long list of drug names can feel overwhelming. Here they're grouped the way care teams usually think about them, so you and your family can find where you are.

ℹ️ General information to help you and your loved ones talk with your care team, not medical advice. Read our disclaimer.

Drugs by line of therapy

Which line a drug is used in depends on your cancer's stage, biomarkers, earlier treatment and overall health. Your care team will decide what's right for you. Many drugs are used in more than one line.

🌱 Early-stage (before or after surgery)

1️⃣ First-line for advanced cancer

2️⃣ Second-line

➡️ Later lines

Browse prostate cancer drug guides

Akeega (niraparib and abiraterone acetate)Targeted therapy pill (PARP inhibitor + hormone therapy)Erleada (apalutamide)Hormone therapy (androgen receptor inhibitor)Jevtana (cabazitaxel)Chemotherapy Lupron Depot (leuprolide acetate)Hormone therapy (GnRH agonist / ADT)Lynparza (olaparib)Targeted therapy pill (PARP inhibitor)Nubeqa (darolutamide)Hormone therapy (androgen receptor inhibitor)Orgovyx (relugolix)Hormone therapy (GnRH antagonist / ADT)Pluvicto (lutetium Lu 177 vipivotide tetraxetan)Radioligand therapy (PSMA-targeted)Rubraca (rucaparib)Targeted therapy pill (PARP inhibitor)Talzenna (talazoparib)Targeted therapy pill (PARP inhibitor)Taxotere (docetaxel)Chemotherapy (taxane)Xofigo (radium Ra 223 dichloride)Radiopharmaceutical (bone-targeted)Xtandi (enzalutamide)Hormone therapy pill (androgen receptor inhibitor)Zytiga (abiraterone acetate)Hormone therapy (androgen synthesis inhibitor)

More treatment options →

Back to the prostate cancer overview.

Written by the Cancer Side Effects Guide team from FDA labels and leading cancer centers. Not medical advice. · Last updated: October 15, 2026 · How we write

Not medical advice. This page is general information to help you talk with your care team. It can't replace advice from your doctor or nurse. If you have a fever of 100.4°F (38°C) or higher during treatment, or any symptom that worries you, call your care team now. In an emergency, call 911.